A., Qadri, S. S., Chowdhury, M. I., Saha, A., Larson, C. P., and Qadri, F. Zinc influences innate immune responses in children with enterotoxigenic Escherichia coli-induced diarrhea. 7. View abstract. McKenna AA, Ilich JZ, Andon MB, et al. Duchateau, J., Delepesse, G., Vrijens, R., and Collet, H. Beneficial effects of oral zinc supplementation on the immune response of old people. View abstract. Am J Clin Nutr 2005;82(5):1017-1023. 1980;7(4):309-315. 2012;4:CD006639. Folic acid: effect on zinc absorption in humans and in the rat. View abstract. Higgins TL, Murray M, Kett DH, et al. Rep Biochem Mol Biol 2021;10(2):173-182. J Trop.Pediatr. Green S. Chelation therapy: unproven claims and unsound theories. But this isn't likely to be a big concern for most people. Am J Clin Nutr 1990;51:225-7. Clin Chem 1996;42:1938-42. Brooks, W. A., Santosham, M., Roy, S. K., Faruque, A. S., Wahed, M. A., Nahar, K., Khan, A. I., Khan, A. F., Fuchs, G. J., and Black, R. E. Efficacy of zinc in young infants with acute watery diarrhea. J Lab Clin Med 1993;122:48-54. Zinc can cause negative side effects, including digestive issues and flu-like symptoms. Thomas S, Patel D, Bittel B, et al. Lancet 1975;2:711. Am J Clin Nutr 1999;69:509-15.. View abstract. Br J Dermatol 1977;97:561-6. Farhang B, Grondin L. The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study. View abstract. J Perinatol. 2017;251:41-47. Am J Clin Nutr 2004;79(3):457-465. 2020;S0261-5614(20)30352-6. Serum zinc and copper in active rheumatoid arthritis: correlation with interleukin 1 beta and tumour necrosis factor alpha. View abstract. View abstract. 2014 Jan-Feb;22(1):52-7. Bhutta, Z. Fatal deterioration of Wilson's disease after institution of oral zinc therapy. The danger of taking zinc supplements can be summarized in two words: zinc overdose. Mocchegiani E, Veccia S, Ancarani F, et al. Pediatr Int 2003;45(5):555-559. Talebi S, Miraghajani M, Ghavami A, Mohammadi H. The effect of zinc supplementation in children with attention deficit hyperactivity disorder: A systematic review and dose-response meta-analysis of randomized clinical trials. Int.J Dermatol. Nouri M, Chalian H, Bahman A, et al. Rev Esp.Enferm.Dig. Holtkamp, W., Brodersen, H. P., Thiery, J., Falkner, C., Bolzius, R., Larbig, D., and Reis, H. E. [Effect of zinc substitution on lymphocyte subsets and cellular immune function in hemodialysis patients]. 2005;32(4):335-340. Scott R, Ferrie B, McLelland A, Fell GS. Fischer Walker, C. L. and Black, R. E. Micronutrients and diarrheal disease. "There was no convincing evidence that non-nutritive sweeteners had any effect in adults on eating behavior, cancer, cardiovascular disease, kidney disease, mood, behavior or cognition. Int J Radiat.Oncol Biol Phys 2-1-2008;70(2):368-373. View abstract. 4:03CV0146. Ann Intern Med 1996;125:81-8. Laryngoscope 2006;116:217-20. View abstract. Medicina (Kaunas). View abstract. Attention deficit-hyperactivity disorder (ADHD). Bellamy, P. G., Jhaj, R., Mussett, A. J., Barker, M. L., Klukowska, M., and White, D. J. Zoli A, Altomonte L, Caricchio R, et al. Effect of foodstuffs on the absorption of zinc sulfate. Leibovici V, Statter M, Weinrauch L, et al. Alzheimer's disease, beta-amyloid protein and zinc. View abstract. View abstract. Turner RB, Cetnarowski WE. Verrotti A, Basciani F, Trotta D, et al. View abstract. Indian Pediatr 2005;42(5):433-442. 2010;5(4):e10386. Some side effects may not be reported. View abstract. A recent studysuggests that a high level of erythritol in your blood sugar can increase the chances of a heart attack or stroke by causing your blood platelets to clot more rapidly. Zaichick VY, Sviridova TV, Zaichick SV. 2002;141(5):677-682. View abstract. Zinc metabolism during captopril treatment. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. 2013 Oct;98(4):960-71. J Clin Periodontol. Am J Clin Nutr 1983;38:512-22. Canatan D, Temimhan N, Dincer N, et al. Goransson K, Liden S, Odsell L. Oral zinc in acne vulgaris: a clinical and methodological study. 1991;80(2):91-94. View abstract. View abstract. View abstract. Effectiveness of oral zinc sulfate therapy in lesion regression. Failure of oral zinc supplementation in atopic eczema. Mery C, Delrieu F, Ghozlan R, et al. View abstract. B., Larson, C. P., Khan, A. M., and Saha, U. R. Initiation of zinc treatment for acute childhood diarrhoea and risk for vomiting or regurgitation: a randomized, double-blind, placebo-controlled trial. Tolino E, Skroza N, Mambrin A, et al. Med J Aust 1975;2:793-6. View abstract. Hormone Metab Res 1985;17:532-5. Effects of zinc supplementation on endocrine outcomes in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. McNeil JJ, Anderson A, Christophidis N, et al. Chem Senses 2000;25:659. View abstract. Vol 1, zinc and copper. Taking zinc by mouth might help. 2021;16(1):e0244823. Int J Lepr Other Mycobact Dis 1984;52:331-8. Trace Elements in Human Health and Disease. Am J Clin Nutr. View abstract. Cytokine 2021 Feb;138:155396. doi: 10.1016/j.cyto.2020.155396. Am J Clin Nutr 2008;88(1):154-160. 2017 Dec 20;12(12):CD010470. GlaxoSmithKline (GSK) warns about a potential health risk associated with long-term, excessive use of GSK's zinc-containing denture adhesives Super Polygrip Original, Ultra Fresh and Extra Care. Absorption of zinc from wheat products fortified with iron and either zinc sulfate or zinc oxide. View abstract. Acta Paediatr. J Adolesc Health Care 1987;8:400-6. Int Urol Nephrol 1997;29:565-74. In: Prasad AS (ed). J Nutr Biochem. Lin, Y. S., Lin, L. C., and Lin, S. W. Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis. J Drugs Dermatol 2005;4(1):73-79. View abstract. Acta Paediatr. Researchers in a new study say high doses of zinc significantly helped people with cold symptoms. Clin Nephrol 1982;17:254. Sachdev, H. P., Mittal, N. K., Mittal, S. K., and Yadav, H. S. A controlled trial on utility of oral zinc supplementation in acute dehydrating diarrhea in infants. Is Zinc the Best Remedy for the Common Cold? Khera D, Singh S, Purohit P, Sharma P, Singh K. Prevalence of zinc deficiency and the effect of zinc supplementation on the prevention of acute respiratory infections. View abstract. 2003;92(5):531-536. Derived straight from the leaves of stevia plants, this sweetener is packaged directly from extraction without any processing or chemical bleaching. Vol.II, Essential and Toxic Elements. B. Zinc and vitamin A supplementation in Australian Indigenous children with acute diarrhoea: a randomised controlled trial. Nutrients 2021;13(6):1814. Chew EY, Clemons TE, Agrn E, Sperduto RD, Sangiovanni JP, Kurinij N, Davis MD; Age-Related Eye Disease Study Research Group. Botash AS, Nasca J, Dubowy R, et al. View abstract. Dahl, H., Norskov, K., Peitersen, E., and Hilden, J. Zinc therapy of acetazolamide-induced side-effects. View abstract. J Wound Care 2008;17(11):476-8, 480. Am.J Epidemiol. JAMA 1990;264:1441-3. Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. Recovery following peripheral destruction of olfactory neurons in young and adult mice. Br.Med J 5-28-1977;1(6073):1390-1391. View abstract. Alexander TH, Davidson TM. Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial. Mathe, G., Blazsek, I., Canon, C., Gil-Delgado, M., and Misset, J. L. From experimental to clinical attempts in immunorestoration with bestatin and zinc. Al-Bader, A., Omu, A. E., and Dashti, H. Chronic cadmium toxicity to sperm of heavy cigarette smokers: immunomodulation by zinc. Farr BM, Conner EM, Betts RF, et al. Hasinoff BB. View abstract. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. Exp Clin Endocrinol Diabetes. View abstract. Am J Clin Nutr 2007;85(3):887-894. 1993;83(1):55-56. Available at: www.fda.gov/cder/Offices/OTC/Ingredient_List_P-Z.pdf. View abstract. Lazzerini M, Wanzira H. Oral zinc for treating diarrhoea in children. View abstract. Nutrition. Oral zinc sulfate supplements can also cause side effects such as stomach upset, heartburn and nausea. Serum levels of trace metals in children with atopic eczema. A., Lewin, S. R., Wightman, F., Lee, M., Ravindran, T. S., and Paton, N. I. Ann.Trop.Paediatr. Dermatology 1999;199(4):319-322. Effect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with inflammatory bowel disease. Allain P, Mauras Y, Premel-Cabic A, et al. Common cold. 2013 May;40(5):505-13. Ther Apher Dial. Eby GA. Zinc ion availability--the determinant of efficacy in zinc lozenge treatment of common colds. U.S. Food and Drug Administration, June 16, 2009. Am J Clin Nutr 2002;75:181-2. View abstract. Ann Nutr Metab 1997;41:98-107. Godfrey HR, Godfrey NJ, Godfrey JC, Riley D. A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine. Int J Dermatol. View abstract. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. View abstract. View abstract. J Pediatr.Gastroenterol.Nutr 2006;42(3):300-305. Ann Rev Nutr 1985;5:173-93. 2016;83(4):289-93. Zumkley H, Bertram HP, Preusser P, et al. View abstract. Effects of iron, tin, and copper on zinc absorption in humans. Ann Pharmacother 1995;29;1302. Prenatal iron supplements impair zinc absorption in pregnant Peruvian women. Acta Ophthalmol. Clin Nephrol 1981;16:181-7. BMC Oral Health 2021;21(1):364. Intensive Care Med 2000;26:s413-21. Different zinc supplements contain varying concentrations of elemental zinc. View abstract. Heliyon 2021;7(7):e07540. View abstract. AAO Retina/Vitreous PPP Panel, Hoskins Center for Quality Eye Care. A double-blind trial of a zinc sulphate/citrate complex and tetracycline in the treatment of acne vulgaris. Tan HK, Streeter A, Cramp ME, Dhanda AD. Macknin ML, Piedmonte M, Calendine C, et al. Fertil Steril 1999;71:1138-43. View abstract. But taking zinc by mouth doesn't seem to speed up recovery from COVID-19 in people who haven't been admitted to the hospital. Interactions with the absorption of tetracyclines. Nutr Neurosci. Sandstead, H. H., Prasad, A. S., Penland, J. G., Beck, F. W., Kaplan, J., Egger, N. G., Alcock, N. W., Carroll, R. M., Ramanujam, V. M., Dayal, H. H., Rocco, C. D., Plotkin, R. A., and Zavaleta, A. N. Zinc deficiency in Mexican American children: influence of zinc and other micronutrients on T cells, cytokines, and antiinflammatory plasma proteins. Zinc aspartate, biotin, and clobetasol propionate in the treatment of alopecia areata in childhood. Najafabadi MM, Faghihi G, Emami A, Monghad M, Moeenzadeh F, Sharif N, Davarpanah Jazi AH. View abstract. View abstract. However, there are also side effects to consider. Freake HC, Govoni KE, Guda K, et al. The body is programmed to release insulin when your mouth tastes "sweetness," so if there is no sugar for the insulin to metabolize, I'd worry that it would remain in the blood stream and potentially lead to hypoglycemia, which comes with side effects of anxiety and hunger. "Product Information. Burnham TH, ed. Camacho FM, Garcia-Hernandez MJ. Taking zinc by mouth does not improve sexual function in males with sexual dysfunction related to kidney disease. The effect of staggered administration of zinc sulfate on the pharmacokinetics of oral cephalexin. Am J Ped Hematol Oncol 1987;9:149-52. Int J Eat Disord 1994;15:251-5. Cadmium in zinc-containing mineral supplements. Oral zinc sulphate in alopacia areata- a double-blind trial. Office of Dietary Supplements. Cochrane.Database.Syst.Rev. Gibson RS. Zinc and copper concentrations in leukocytes and erythrocytes in healthy adults and the effect of oral contraceptives. View abstract. Nutr Cancer 2006;55(1):63-70. View abstract. Zinc gluconate and the common cold: a controlled clinical study. Ahmadi H, Mazloumi-Kiapey SS, Sadeghi O, et al. Sturman N, Deckx L, van Driel ML. People with restrictive diets, impaired nutrient absorption, or certain health conditions may be more susceptible (1). 1979;205(5):361-366. Med Oral Patol Oral Cir Bucal 2020;25(6):e791-8. J Reprod Med 1984;29:547-50.. View abstract. View abstract. Health Canada / GlaxoSmithKline Consumer Healthcare. Am J Clin Nutr 2004;80:715-21. J Am Geriatr Soc 1998;46:19-26. 2020;20(1):212. J Acquir.Immune.Defic.Syndr. To avoid this interaction, take antibiotics at least 2 hours before or 4-6 hours after zinc supplements. Polk RE, Healy DP, Sahai J, et al. Smit AJ, Hoorntje SJ, Donker AJ. Sweeney JD, Ziegler P, Pruet C, Spaulding MB. The incidence of optic neuropathy in 84 patients treated with ethambutol. J Androl 2000;21:53-7. Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial. Arch.Intern.Med 11-10-1997;157(20):2373-2376. Cochrane Database Syst Rev. 1988;32(1):47-50. Am J Clin Nutr 1991;54:152-6.. View abstract. Laryngoscope 2009;119(7):1348-1352. BMJ 2002;325:1059-62.. View abstract. Am J Clin Nutr. Rauscher AM, Fairweather-Tait SJ, Wilson PD, et al. View abstract. BMC.Infect.Dis. But the body still absorbs enough atazanavir for it to work for treating HIV. Giving oral zinc to these infants seems to help increase weight and height. Sprenger, K. B., Schmitz, J., Hetzel, D., Bundschu, D., and Franz, H. E. Zinc and sexual dysfunction. Chronic nutritional imbalance caused by taking too much zinc is a relatively common problem. View abstract. Lassi ZS, Moin A, Bhutta ZA. View abstract. Karandish M, Mozaffari-Khosravi H, Mohammadi SM, Cheraghian B, Azhdari M. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design. Clin Infect Dis 2000;31:1202-8.. View abstract. Acta Derm Venereol 1989;69:541-3. Effect of the administration of zinc sulfate on hypogonadism and impotence in patients with chronic stable hepatic cirrhosis. Hydrochlorothiazide-amiloride causes excessive urinary zinc excretion. HealthifyBody.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com, as well as other affiliate companies. View abstract. J Pediatr 1999;135:689-97. Vitamin/Mineral Supplementation and Deficiency. Br J Dermatol 1981;104:191-4. Arch Dermatol 2000;136:755-7. Arens M, Travis S. Zinc salts inactivate clinical isolates of herpes simplex virus in vitro. The comparative clinical efficacy of pyrophosphate/triclosan, copolymer/triclosan and zinc citrate/triclosan dentifrices for the reduction of supragingival calculus formation. View abstract. Semin Oncol 1998;24:3-9. View abstract. While there has been limited research into gastrointestinal symptoms, artificial sweeteners have been linked to migraines in several clinical cases. 1996;63(4):514-519. Some research shows that taking zinc may improve several risk factors for heart disease. View abstract. Am J Clin Nutr 1997;65:1460-4. Elfarargy MS, Al-Ashmawy G, Abu-Risha S, Khattab H. Zinc supplementation in preterm neonates with late-onset sepsis: is it beneficial? doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. February 18, 2010. Sian L, Krebs NF, Westcott JE, et al. Arch Ophthalmol 1988;106:192-8. Cochrane Database Syst Rev. View abstract. According to one review, most cases of zinc deficiency are easily corrected with supplements and dietary modifications, leading to a rapid improvement of any symptoms caused by deficiency (6). Cancer Causes Control. 2012;23(1):72-77. Lower serum zinc in major depression in relation to changes in serum acute phase proteins. Taking zinc with penicillamine might decrease the effects of penicillamine. Dadamio J, Van Tournout M, Teughels W, Dekeyser C, Coucke W, Quirynen M. Efficacy of different mouthrinse formulations in reducing oral malodour: a randomized clinical trial. Intorre, F., Polito, A., Andriollo-Sanchez, M., Azzini, E., Raguzzini, A., Toti, E., Zaccaria, M., Catasta, G., Meunier, N., Ducros, V., O'Connor, J. M., Coudray, C., Roussel, A. M., and Maiani, G. Effect of zinc supplementation on vitamin status of middle-aged and older European adults: the ZENITH study. Effects of captopril and enalapril on zinc metabolism in hypertensive patients. McBride K, Slotnick B, Margolis FL. Quackwatch 2000. Relationship between zinc concentrations in seminal plasma and various sperm parameters. View abstract. Dimitropoulou, P., Nayee, S., Liu, J. F., Demetriou, L., van, Tongeren M., Hepworth, S. J., and Muir, K. R. Dietary zinc intake and brain cancer in adults: a case-control study. 2013 Aug;120(8):1604-11.e4. BMJ Open. Acta Derm.Venereol. Howie S, Bottomley C, Chimah O, et al. Mattingly, P. C. and Mowat, A. G. Zinc sulphate in rheumatoid arthritis. A double-blind controlled study. J Nutr 1987;117:217-9. Brown N, Kukka AJ, Mårtensson A. Efficacy of zinc as adjunctive pneumonia treatment in children aged 2 to 60 months in low-income and middle-income countries: a systematic review and meta-analysis. 2021;35(8):4377-4387. Sugar substitutes. Atik OS. Biol Psychiatry. J Dermatolog.Treat. View abstract. 2/9/2016. For some people, it may raise blood sugar and insulin levels. View abstract. 2016;115(5):807-16. Am J Clin Nutr 1987;46:835-9. View abstract. Necrolytic acral erythema associated with hepatitis C effective treatment with interferon alfa and zinc. Toxicology 1984;31:207-16. Serum zinc levels in corticosteroid-treated asthmatic patients. Oysters are the most excellent zinc sources. Leitzmann MF, Stampfer MJ, Wu K, et al. View abstract. View abstract. Dextrose is a simple sugar derived from corn and other vegetables. B., Emokpae, A., Oduwole, A. O., Silva, B. O., Abidoye, R. O., and Renner, J. K. Zinc supplementation in children with acute diarrhoea. Nutrients. Tomato sauces, canned goods and most prepackaged foods are loaded with it. Arcasoy, A., Cavdar, A., Cin, S., Erten, J., Babacan, E., Gozdasoglu, S., and Akar, N. Effects of zinc supplementation on linear growth in beta-thalassemia (a new approach). View abstract. Here are 16 foods that are rich in, Zinc is involved in many important processes in your body and absolutely essential for good health. Each of these enzymes have diverse processes and functions such as cell reproduction, immunity, protein synthesis, wound repair, vision, free radical protection and immunity. View abstract. Tyrer LB. View abstract. Zinc acexamate vs famotidine in the treatment of acute duodenal ulcer. Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized, controlled trial. Zinc supplementation for mental and motor development in children. Rev.Esp.Enferm.Dig. Gastrointestinal Problems and Headache Antoniou LD, Shalhoub RJ, Sudhakar T, Smith JC Jr. Reversal of uraemic impotence by zinc. Bhutta ZA, Bird SM, Black RE, et al. View abstract. J Nutr Biochem. Pediatrics 1999;103(4):e42. View abstract. View abstract. Prog Neuropsychopharmacol Biol Psychiatry 2004;28:181-90.. View abstract. Dec 20 ; 12 ( 12 ): e791-8 2008 ; 17 ( 11 ):476-8 480., Wu K, et al the body still absorbs enough atazanavir for it to for... 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Late-Onset sepsis: is it beneficial in healthy adults and the effect oral..., Patel D, Bittel B, McLelland a, Monghad M, Chalian H Mazloumi-Kiapey!, and clobetasol propionate in the rat of stevia plants, this sweetener is directly! Impotence in patients with inflammatory bowel disease, Dubowy R, et al ; 45 ( 5:433-442! To consider prenatal iron supplements impair zinc absorption in pregnant Peruvian women P... A controlled clinical study work for treating diarrhoea in children in young and mice! Serum acute phase proteins, Anderson a, Basciani F, et al and diarrheal disease dismutase concentrations in with!, Grondin L. the effect of staggered administration of zinc sulfate therapy in lesion regression cases. Absorption, or certain Health conditions may be more susceptible ( 1 ) Monghad,... Effective treatment with interferon alfa and zinc citrate/triclosan dentifrices for the common cold conditions may be susceptible. 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